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Cover image for product 3527340408
Hilfiker
ISBN: 978-3-527-34040-8
Hardcover
500 pages
February 2019, ©2017
List Price: 215.00 USD
28,380,000 IRR افزودن به سبد
  • Description
  • Table of Contents
  • Author Information
Completely revised and re-organized to highlight the latest developments and quality by design concepts, this new edition covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues and regulatory applications.
As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development in general and polymorphism in particular. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are described in detail, and a case study on solid-state development processes in industry is also provided.
Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid state chemistry.
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