Translational Toxicology and Therapeutics: Windows of Susceptibility in Reproduction and Cancer

This book links the disciplines of toxicology and therapeutics, relating toxicant exposure and genetic mechanisms to human health and development. The chapters explain specific cellular and molecular targets of known toxicants and offer a systematic approach to identify mutagenic and reproductive toxicants. Written by leading research scientists; the chapters cover cancer and mutation causes, toxicant exposures, gene-environment interactions, toxicant modes-of-action, therapeutic strategies to reduce cancer risk. Readers can use this to develop new animal models and tests to assess toxic impacts – specifically mutation and cancer – on human health.