Patty’s Toxicology was originally published as Patty’s Industrial Hygiene and Toxicology in 1948. Patty's Toxicology has long been recognized as the premier reference for toxicological information on a large number of industrial chemicals that pose potential health hazards to workers and, by extension, consumers of products containing such chemicals. Patty’s Toxicology includes comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it an essential reference.
The 7th edition reorganizes the book to place the key introductory topics in Volume 1. The first volume provides the basic concepts, approaches and vocabulary that recur throughout the rest of the book. There are several new sections to the introductory volume including biotransformation of xenobiotics, toxicokinetics, mitochondrial toxicology, genetic toxicology, cancer risk assessment reproductive and developmental, and the setting of occupational exposure levels.
Other topics added to subsequent volumes include fluorinated compounds used in food packaging such as for non-stick pans as well as for making upholstered furniture, carpets, shoes, mattresses and clothing that are resistant to soil, stains, and water. Other new chapters include flavoring chemicals, flame retardants and engine lubricants. The 7th edition also contains information on plasticizers/phthalates, and exhaust from diesel engines. The section in Patty’s pertaining to agricultural chemicals is reorganized and expanded, including more coverage of pesticides. Topics where there is substantial new research, such as nanomaterials, are significantly enhanced. To retain the focus on toxicology, chapters that cover topics that address occupational hazards that are not toxicologic in nature, such as tuberculosis, have been removed.
