Analytical Characterization of Biotherapeutics

This book serves as a guide to the myriad analytical techniques available to researchers who are either curious about or involved in the characterization of therapeutic proteins and the antigen reagents. The book frames poignant questions necessitating attention during the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules and also presents solutions. From simple recombinant antigen & antibody characterization using standardized analytical tools and informatics solutions, to complex analyses for the increasing complexity of molecular designs such as antibody drug conjugates and bi-specific antibodies, the book helps researchers navigate through the history of the analysis tools & offer insight into some of the up and coming analytical solutions available.

The book aims to provide in a single volume, a collection of cutting-edge analytical strategies for a number of bio-therapeutics from research tools to therapeutic molecules. Each chapter is written by a recognised expert in their field, covering in detail current and cutting edge approaches to fully characterize these bio therapeutics.