Comprehensive Chromatography in Combination with Mass Spectrometry

A clear, concise, and all-encompassing approach to comprehensive chromatography methodologies

An excellent primer to the field of comprehensive chromatography (CC), this book provides a detailed description of various multidimensional chromatographic separation techniques in an effort to acquaint readers with the fundamentals and possible benefits of multidimensional separations coupled with mass spectrometry—an expanding topic, and one of the most rapidly developing areas in analytical chemistry.

Among the first and most up-to-date books dealing with CC methodologies, this single-volume reference gathers and combines studies from a multitude of scientific literature to discuss a wide range of important topics. In-depth coverage of separation techniques such as comprehensive 2D GC, LC and LC-GC shows how these and various other combinations are ideal for the separation and analysis of complex mixtures in the pharmaceutical, biological, industrial, environmental, and clinical fields. Other subjects explored in this text include:

• The theoretical considerations of multidimensional gas and liquid chromatography

• The history, evolution, and optimization aspects of comprehensive two-dimensional gas and liquid chromatography

• Up-to-date comprehensive chromatography data interpretation technologies

The feedback gained from comprehensive chromatographic techniques, though promising, still remains an emerging contributor to the research field. With the goal of extracting the enormous potential embedded in CC methodologies, Comprehensive Chromatography in Combination with Mass Spectrometry provides insight that takes a great leap forward in advancing exploration into this highly complex—yet highly powerful—analytical tool.